The ITGB3BP Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ITGB3BP. This antibody recognizes Human antigen. The ITGB3BP Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants